What Are Polynucleotides?

Have you noticed the buzz about polynucleotides? You’re not alone! These powerful little molecules are quickly becoming the most popular aesthetic treatment of 2024, and it looks like they will be a sticking around for 2025 too—and for good reason. But what exactly are they, and why is everyone talking about them?

The Science Behind Polynucleotides

Polynucleotides might sound like a complex scientific term, but simply put, they are long chains of nucleotides—the building blocks of DNA and RNA. When used in aesthetics, these molecules work wonders in repairing and regenerating tissue.

Sometimes referred to as The Salmon Sperm Facial, Polynucleotides are derived from salmon DNA (don’t worry, it’s carefully purified!). This means they are highly compatible with the body due to the similarities between salmon and human DNA (who would have thought!).

How Do Polynucleotides Benefit Your Skin?

Within the aesthetics world there’s a movement towards regenerative medicine, over just using Botox and fillers to treat the signs of ageing. Regenerative medicine uses the body’s natural healing process in order to restore youthful skin. Polynucleotides act as messengers, signalling your skin to repair itself.

Polynucleotides work their magic by promoting:

1. Collagen Stimulation

By activating fibroblasts (the cells responsible for collagen production), polynucleotides help improve skin elasticity and firmness. Over time, this reduces fine lines and sagging.

2. Skin Hydration

Polynucleotides are hydrophilic, meaning they attract and retain water in the skin. This results in plumper, more hydrated skin.

3. Tissue Repair

Whether it’s sun damage, acne scars, or general ageing, polynucleotides support tissue regeneration by encouraging cell turnover and healing.

4. Anti-Inflammatory Effects

They calm inflammation, making them an excellent choice for sensitive or reactive skin.

Are Polynucleotides Right for You?

Polynucleotide-based treatments are versatile and suitable for a range of concerns, including:

• Fine lines and wrinkles.

• Skin laxity (sagging).

• Dehydrated or dull skin.

• Acne scars and post-inflammatory pigmentation.

Treatments can be tailored to your skin’s specific needs and are often combined with other procedures like microneedling or Profhilo for enhanced results.

What To Expect From Polynucleotide Treatments

Polynucleotides are most commonly delivered via injectables, where the product is placed directly into the dermis. A course of treatments is typically recommended for the best results.

While they’re not a “quick fix” (results build over time), patients often notice improved texture, hydration, and radiance after just a few sessions. Think of polynucleotides as a long-term investment in healthier, younger-looking skin.

Ready to Try Polynucleotides?

Polynucleotides are a fantastic option for those looking to enhance their skin’s natural beauty without resorting to more invasive treatments. Curious to find out if they’re right for you? Book a consultation, and we’ll discuss how they can fit into your personalised skincare plan.

Sources:

• DermNet NZ (2023): Polynucleotide Benefits for Skin.

• Aesthetic Medicine Journal (2022): Role of Polynucleotides in Skin Repair.

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